New brachytherapy treatment planning system was developed using 3D-Slicer as front-end software. The proposed MC-PRISM (MonteCarlo based Prostate bRachytherapy plannIng System) was wrapped into 3D-Slicer. MC-PRISM allows fast Monte Carlo (MC) simulation with local or distant calculation on server. The dose provides by MC-PRISM is fully personalized according US and CT images of the patient. MC-PRISM is used to automatically perform the inverse planning for whole gland, hemi-gland, boost and focused prostate brachytherapy. The resulted plan do not need to be tune by dosimetrist thanks to the DVH-based optimization and the cost function based on the AAPM TG-137 dosimetric criteria. Finally, this new TPS allows a complete MC-based inverse planning in less than 1 min using a standard CPU (Intel Core i7 with 4 cores).

Publications:

1. Mountris K A, Visvikis D, Bert J, (2018). DVH-based Inverse Planning using Monte Carlo Dosimetry for LDR Prostate Brachytherapy International Journal of Radiation Oncology - Biology, Physics
2. Behlouli A, Visvikis D, Bert J, (2018). Improved Woodcock tracking on Monte Carlo simulations for medical applications Physics in Medicine and Biology 63 pp 225005
3. Behlouli A, Bert J, Visvikis D, (2017). Improved Woodcock tracking on Monte Carlo simulations for medical applications International Conference on Monte Carlo Techniques for Medical Applications (Oral presentation)
4. Mountris K A, Bert J, Boussion N, Valeri A, Schick U, Visvikis D, (2017). ORACLE: A DVH-based inverse planning system for LDR prostate brachytherapy using MC dosimetry International Conference on Monte Carlo Techniques for Medical Applications (Oral presentation)
5. Behlouli A, Bert J, Visvikis D, (2017). Improved Woodcock tracking on Monte Carlo simulations for medical applications IEEE Nuclear Science Symposium and Medical Imaging Conference (Oral presentation)
6. Mountris K A, Bert J, Boussion N, Valeri A, Schick U, Visvikis D, (2018). DVH-based optimization of LDR prostate brachytherapy using GPU-accelerated MC dosimetry SURGETICA (Oral presentation)
7. Mountris K A, Bert J, Visvikis D, (2018). LDR prostate brachytherapy inverse planning including dose-volume relation and tissue heterogeneity European Society for Radiotherapy & Oncology (ESTRO)
8. Bert J and Visvikis D, (2018). Smooth mesh for accurate Monte Carlo simulation in medical application IEEE Nuclear Science Symposium and Medical Imaging Conference (Oral presentation)

Software:

9. MC-PRIMS: Monte-Carlo based Prostate bRachytherapy planning SysteM, IDDN.FR.001.040010.000.S.P.2020.000.31230